HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Saita, E. Articles by Taya, K. Search for Related Content PubMed PubMed Citation Articles by Saita, E. Articles by Taya, K.

¹ Department of Basic Veterinary Science, The United Graduate School of Veterinary Science, Gifu University, Gifu 501-1193, Japan;
² Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan;
³ Division of Wild Animal Medicine, Nippon Veterinary and Animal Science University, Tokyo 180-8602, Japan;
⁴ Nippon Professional School of Medical Technology, Tokyo 180-8602, Japan;
⁵ Japan Wildlife Research Center, Tokyo 110-8676, Japan
⁶ Corresponding author (email: taya{at}cc.tuat.ac.jp)

ABSTRACT:   We compared morphologic changes in thyroid glands of great cormorants (Phalacrocorax carbo) from the Tokyo Bay and Lake Biwa areas in Japan with presence of residues of polychlorinated dibenzo-dioxins (PCDDs), polychlorinated dibenzo-furans (PCDFs), and coplanar polychlorinated biphenyls (Co-PCBs). Prominent morphologic changes in thyroid glands included increased density of small follicles and increased number of epithelial cells surrounding follicular lumens. The extent of morphologic changes in the thyroid gland was higher in cormorants captured from Tokyo Bay than in those captured from Lake Biwa. Increased thyroid change in cormorants from the Tokyo Bay area was associated with significantly higher levels of PCDFs and Co-PCBs. Thus, we suggest that morphologic changes in thyroid glands from the cormorants are associated with increased levels of dioxin contamination in Japan.
  Key words:  Dioxins, great cormorant, organochlorines, Phalacrocorax carbo, thyroid gland, Tokyo Bay, Japan.

This article has been cited by other articles:

				M. Boas, U. Feldt-Rasmussen, N. E Skakkebaek, and K. M Main Environmental chemicals and thyroid function. Eur. J. Endocrinol., May 1, 2006; 154(5): 599 - 611. [Abstract] [Full Text] [PDF]

				P. Pocar, T. Klonisch, C. Brandsch, K. Eder, C. Frohlich, C. Hoang-Vu, and S. Hombach-Klonisch AhR-Agonist-Induced Transcriptional Changes of Genes Involved in Thyroid Function in Primary Porcine Thyrocytes Toxicol. Sci., February 1, 2006; 89(2): 408 - 414. [Abstract] [Full Text] [PDF]