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To investigate a possible link of malignant hyperthermia to capture myopathy, between June 1990 and July 1993 we anesthetized four black-tailed deer (Odocoileus hemionus columbianus) and challenged them with halothane and succinylcholine. Halothane had no significant effect on oxygen consumption. Succinylcholine significantly (P < 0.05) increased cardiac output (mean +/- SD), from 2.94 +/- 1.05 l/min to 5.26 +/- 1.79 l/min, and oxygen consumption, from 5.5 +/- 2.1 ml/kg/min to 10.1 +/- 2.9 ml/kg/min. Muscle biopsy specimens tested for malignant hyperthermia susceptibility responded normally to halothane and caffeine. We conclude that these deer did not experience malignant hyperthermia; suggesting no link to capture myopathy.
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L. C. R. Meyer, L. Fick, A. Matthee, D. Mitchell, and A. Fuller HYPERTHERMIA IN CAPTURED IMPALA (AEPYCEROS MELAMPUS): A FRIGHT NOT FLIGHT RESPONSE J. Wildl. Dis., April 1, 2008; 44(2): 404 - 416. [Abstract] [Full Text] [PDF] |
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