Blood samples were taken from 23 swift foxes (Vulpes velox) which were to be used in a reintroduction program. The foxes originated from two different captive breeding programs: one at the Calgary Zoo (CZ) and one at the Wildlife Reserve of Western Canada (WRWC). Several differences between swift fox and domestic canine hematology were seen, including an increased number of smaller red blood cells and lower absolute leukocyte counts in swift foxes. Serum glutamic pyruvic transaminase was higher than in the domestic canine normal range while serum creatinine values were lower. Hemoglobin, serum potassium, total protein, globulin in the two groups (CZ and WRWC) were statistically different as were male versus female mean corpuscular volume values.