Baseline body temperatures (BT), heart rates (HR) and respiratory rates (RR) were obtained from Alaskan moose (Alces alces gigas Miller) at the Moose Research Center (MRC), Alaska. Excitability, seasons and drugs influenced the values to varying degrees. Excitability was the most influential factor. Safe expected ranges were: BT 38.4 to 38.9 C, HR 70 to 91 beats/min (b/min), and RR 13 to 40 respirations/min (r/min). These ranges incorporated all seasons, a central nervous system depressant drug and a paralyzing drug. Values which may be considered critical and an indication that corrective action should be taken include: BT 40.2 C, HR 102 b/min, and RR 40 r/min. It is recommended that persons trained in monitoring vital signs be on hand during moose capture and immobilization procedures.