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Journal of Wildlife Diseases, 16(3), 1980, pp. 343-346
© Wildlife Disease Association  1980
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Apparent drug resistance to the organophosphate dimethyl (2,2,2-trichloro-1-hydroxyethyl) phosphonate by monogenetic trematodes

BA Goven, JP Gilbert, and JB Gratzek


ABSTRACT

Gyrodactylus elegans on goldfish, (Carassius auratus) from a commercial farm were resistant to recommended dosages of dimethyl (2,2,2-trichloro-1-hydroxyethyl) phosphonate. Controlled experiments suggest that a dosage 100 times the commonly recommended minimal dosage (.25 mg/l) was required to remove trematodes. A hypothesis is proposed to account for the development of drug resistant trematodes based on the life cycle of the parasites and continual drug exposure.




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Copyright © 1980 by the Wildlife Disease Association.